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1

ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression

Dakshina M. Jandhyala, Amrita Ahluwalia, Tom Obrig, Cheleste M. Thorpe

Journal:

Cellular Microbiology

Year:

2008

Language:

english

File:

PDF, 260 KB

english, 2008

2

An A2Aadenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models

Christopher C Moore, Edward N Martin, Grace H Lee, Tom Obrig, Joel Linden, W Michael Scheld

Journal:

BMC Infectious Diseases

Year:

2008

Language:

english

File:

PDF, 263 KB

english, 2008

3

Immunohistologic techniques for detecting the glycolipid Gb3in the mouse kidney and nervous system

Glynis L. Kolling, Fumiko Obata, Lisa K. Gross, Tom G. Obrig

Journal:

Histochemistry and Cell Biology

Year:

2008

Language:

english

File:

PDF, 691 KB

english, 2008

4

Hemolytic uremic syndrome: epidemiology, pathophysiology, and therapy

S. P. Andreoli, Howard Trachtman, David W. K. Acheson, Richard L. Siegler, Tom G. Obrig

Journal:

Pediatric Nephrology

Year:

2002

Language:

english

File:

PDF, 66 KB

english, 2002

5

Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model

Seaner, Regina, Pincus, Seth H, Obrig, Tom G, Roche, James K, Stone, Matthew K, Gross, Lisa K, Lindner, Matthew

Journal:

Laboratory Investigation

Year:

2008

Language:

english

File:

PDF, 773 KB

english, 2008

6

Response to Shiga toxin 1 and 2 in a baboon model of hemolytic uremic syndrome

Richard L. Siegler,Tom G. Obrig,Theodore J. Pysher…

Journal:

Pediatric Nephrology

Year:

2003

Language:

english

File:

PDF, 269 KB

english, 2003

7

Alanyl-glutamine hastens morphologic recovery from 5-fluorouracil–induced mucositis in mice

Benedito A. Carneiro-Filho, Reinaldo B. Oriá, Katie Wood Rea, Gerly A.C. Brito, Jun Fujii, Tom Obrig, Aldo A.M. Lima, Richard L. Guerrant

Journal:

Year:

2004

Language:

english

File:

PDF, 693 KB

english, 2004

8

Pathogenesis of E. coli hemolytic uremic syndrome

Susan A. Kaye, Tom G. Obrig

Journal:

Clinical Microbiology Newsletter

Year:

1996

Language:

english

File:

PDF, 567 KB

english, 1996

9

Inhibition of Peptide Initiation on Reticulocyte Ribosomes by Edeine

Tom Obrig, James Irvin, William Culp, Boyd Hardesty

Journal:

Year:

1971

Language:

english

File:

PDF, 1.18 MB

english, 1971

10

Flavopiridol Induces Apoptosis and Caspase-3 Activation of a Newly Characterized Burkitt's Lymphoma Cell Line Containing Mutant P53 Genes

Aaron P. Rapoport, Michelle Simons-Evelyn, Timothy Chen, Rochel Sidell, Shannon Luhowskyj, Karen Rosell, Tom Obrig, David Hicks, Patricia M. Hinkle, Moon Nahm, Richard A. Insel, Camille N. Abboud

Journal:

Blood Cells, Molecules, and Diseases

Year:

2001

Language:

english

File:

PDF, 328 KB

english, 2001

11

Direct Cytotoxic Effects of Hemorrhagic Toxins from Crotalus ruber ruber and Crotalus atrox on Human Vascular Endothelial Cells, in Vitro

Tom G. Obrig, Chandra B. Louise, Timothy P. Moran, Nobu Mori, Anthony T. Tu

Journal:

Microvascular Research

Year:

1993

File:

PDF, 58 KB

1993

12

Human Renal Microvascular Endothelial Cells as a Potential Target in the Development of the Hemolytic Uremic Syndrome as Related to Fibrinolysis Factor Expression, in Vitro

Chandra B. Louise, Tom G. Obrig

Journal:

Microvascular Research

Year:

1994

File:

PDF, 424 KB

1994

13

The effect of an antiviral peptide on the ribosomal reactions of the peptide elongation enzymes, EF-I and EF-II

Tom G. Obrig, James D. Irvin, Boyd Hardesty

Journal:

Archives of Biochemistry and Biophysics

Year:

1973

Language:

english

File:

PDF, 979 KB

english, 1973

14

Ribonuclease activity associated with the 60S ribosome-inactivating proteins ricin A, phytolaccin and Shiga toxin

Tom G. Obrig, Timothy P. Moran, Robert J. Colinas

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 1.22 MB

english, 1985

15

Human Platelet Aggregation Is Not Altered by Shiga Toxins 1 or 2

Delia Viisoreanu, Renata Polanowska-Grabowska, Sudawadee Suttitanamongkol, Tom G Obrig, Adrian R.L Gear

Journal:

Thrombosis Research

Year:

2000

Language:

english

File:

PDF, 106 KB

english, 2000

16

CXCL1/KC and CXCL2/MIP-2 Are Critical Effectors and Potential Targets for Therapy of Escherichia coli O157:H7-Associated Renal Inflammation

James K. Roche, Tiffany R. Keepers, Lisa K. Gross, Regina M. Seaner, Tom G. Obrig

Journal:

The American Journal of Pathology

Year:

2007

Language:

english

File:

PDF, 2.24 MB

english, 2007

17

Protein composition of L-cell messenger ribonucleoproteins

Tom Obrig, Anna Shen, Suzanne Kwoka, Mary Ann Chudyk

Journal:

Biochemical and Biophysical Research Communications

Year:

1979

Language:

english

File:

PDF, 643 KB

english, 1979

18

The binding of adenosine-3′,5′-monophosphate by messenger ribonucleoprotein-like particles

Tom G. Obrig, Ross S. Antonoff, K. Siena Kirwin, James J. Ferguson Jr.

Journal:

Biochemical and Biophysical Research Communications

Year:

1975

Language:

english

File:

PDF, 418 KB

english, 1975

19

Shiga toxin from Shigella dysenteriae 1 inhibits protein synthesis in reticulocyte lysates by inactivation of aminoacyl-tRNA binding

Brown, J.Edward, Obrig, Tom G., Ussery, Michael A., Moran, Timothy P.

Journal:

Microbial Pathogenesis

Year:

1986

Language:

english

File:

PDF, 1.71 MB

english, 1986

20

Production of cytotoxin by clinical strains of Pseudomonas aeruginosa

Baltch, Aldona L., Obrig, Tom G., Smith, Raymond P., Hammer, Mark C., Conroy, Joseph V., Lutz, Frieder

Journal:

Canadian Journal of Microbiology

Year:

1987

Language:

english

File:

PDF, 703 KB

english, 1987

21

Binding of [125I]Shiga-like Toxin-1 to Human Endothelial Cells: Implications for the Pathogenesis of Shiga Toxin-associated Hemolytic Uremic Syndrome

Louise, Chandra, Moran, Timothy, Lingwood, Clifford, Vecchio, Peter J. Del, Culp, David, Obrig, Tom

Journal:

Year:

1995

Language:

english

File:

PDF, 1.07 MB

english, 1995

22

Mechanism of Clostridium difficile Toxin A–Induced Apoptosis in T84 Cells

Brito, Gerly A. C., Fujji, Jun, Carneiro‐Filho, Benedito A., Lima, Aldo A. M., Obrig, Tom, Guerrant, Richard L.

Journal:

The Journal of Infectious Diseases

Year:

2002

Language:

english

File:

PDF, 307 KB

english, 2002

23

Shiga Toxin 2 Affects the Central Nervous System through Receptor Globotriaosylceramide Localized to Neurons

Obata, Fumiko, Tohyama, Koujiro, Bonev, Adrian D., Kolling, Glynis L., Keepers, Tiffany R., Gross, Lisa K., Nelson, Mark T., Sato, Shigehiro, Obrig, Tom G.

Journal:

The Journal of Infectious Diseases

Year:

2008

Language:

english

File:

PDF, 4.15 MB

english, 2008

24

Escherichia coli Shiga Toxin Mechanisms of Action in Renal Disease

Journal:

Year:

2010

Language:

english

File:

PDF, 149 KB

english, 2010

25

[Methods in Enzymology] Bacterial Pathogenesis Part A: Identification and Regulation of Virulence Factors Volume 235 || [52] Toxins that inhibit host protein synthesis

Year:

1994

Language:

english

File:

PDF, 577 KB

english, 1994

26

Hemolytic-uremic syndrome and enterohemorrhagic Escherichia coli

PICKERING, LARRY K., OBRIG, TOM G., STAPLETON, BRUDER F.

Journal:

Pediatric Infectious Disease

Year:

1994

File:

PDF, 9.67 MB

1994

27

Local Anesthetic-Induced Protection Against Lipopolysaccharide-Induced Injury in Endothelial Cells: The Role of Mitochondrial Adenosine Triphosphate-Sensitive Potassium Channels

de Klaver, Manuela J. M., Weingart, Gregory S., Obrig, Tom G., Rich, George F.

Journal:

Anesthesia & Analgesia

Year:

2006

Language:

english

File:

PDF, 495 KB

english, 2006

28

Specific Interaction of Escherichia coli O157:H7-Derived Shiga-like Toxin II with Human Renal Endothelial Cells

Chandra B. Louise and Tom G. Obrig

Journal:

The Journal of Infectious Diseases

Year:

1995

Language:

english

File:

PDF, 845 KB

english, 1995

29

Role of Shiga/Vero Toxins in Pathogenesis

Obata, Fumiko, Obrig, Tom

Journal:

Microbiology Spectrum

Year:

2014

Language:

english

File:

PDF, 504 KB

english, 2014

30

Distribution of Gb3 Immunoreactivity in the Mouse Central Nervous System

Obata, Fumiko, Obrig, Tom

Journal:

Year:

2010

Language:

english

File:

PDF, 760 KB

english, 2010

31

Shiga toxin 2 and lipopolysaccharide cause monocytic THP-1 cells to release factors which activate platelet function

Guessous, Fadila, Marcinkiewicz, Marek, Polanowska-Grabowska, Renata, Keepers, Tiffany, Obrig, Tom, Gear, Adrian

Journal:

Thrombosis and Haemostasis

Year:

2005

File:

PDF, 412 KB

2005